Depression can be a silent struggle, often hidden behind smiles and daily routines. For those walking through this emotional valley, prayer can be a powerful source of healing, hope, and strength.
Prayer For Depressed Person
This collection of heartfelt prayers is written for anyone battling depression or for loved ones interceding on their behalf. May these words bring comfort, peace, and a reminder that God is always near—even in the darkest moments.
1. A Prayer for Inner Peace
Dear God, I lift up this weary soul battling depression. Please pour Your peace that surpasses understanding into their heart. Calm their anxious thoughts and soothe their troubled mind. Let them feel Your presence as a gentle embrace, easing their burdens. Help them find rest in Your love, knowing You are near. Replace their despair with hope and their sorrow with comfort. Guide them to still waters, where they can find solace. Thank You for Your endless compassion. Amen.
Philippians 4:7
“And the peace of God, which transcends all understanding, will guard your hearts and your minds in Christ Jesus.”
2. A Prayer for Renewed Hope
Heavenly Father, I pray for one whose hope feels lost in the shadows of depression. Shine Your light into their darkness, reminding them of Your promises. Rekindle their spirit with the assurance that You have plans for their future. Let them see glimpses of joy even in pain. Strengthen their heart to trust in Your goodness. May they find courage to face each day, knowing You are their anchor. Thank You for never giving up on them. Amen.
Jeremiah 29:11
“For I know the plans I have for you,” declares the Lord, “plans to prosper you and not to harm you, plans to give you hope and a future.”
3. A Prayer for Emotional Healing
Loving God, I come before You for someone hurting deeply. Their heart is heavy with depression, and they need Your healing touch. Mend their broken emotions and restore their joy. Help them release their pain to You, trusting in Your care. Surround them with love and understanding. Let them feel Your grace washing over their wounds. Guide them toward wholeness, step by step. Thank You for being their healer and comforter. Amen.
Psalm 147:3
“He heals the brokenhearted and binds up their wounds.”
4. A Prayer for Strength in Weakness
Dear Lord, I pray for the one who feels weak under the weight of depression. Be their strength when they cannot stand alone. Fill them with Your power to endure and overcome. Let them lean on You, finding resilience in Your love. Help them face each moment with courage, knowing You uphold them. Replace their exhaustion with Your energy. Thank You for being their rock and refuge. Amen.
Isaiah 40:29
“He gives strength to the weary and increases the power of the weak.”
5. A Prayer for Comfort in Sorrow
Gracious Father, I seek Your comfort for one engulfed in sorrow. Depression has clouded their days, but You are the God of all comfort. Wrap them in Your loving arms, easing their pain. Let them feel Your presence as a warm embrace. Help them find solace in Your promises. Dry their tears with Your tenderness and fill their heart with peace. Thank You for being near to the brokenhearted. Amen.
2 Corinthians 1:3-4
“Praise be to the God and Father of our Lord Jesus Christ, the Father of compassion and the God of all comfort, who comforts us in all our troubles.”
6. A Prayer for Clarity of Mind
Dear God, I pray for the one whose mind is foggy with depression. Clear the confusion and bring clarity to their thoughts. Help them focus on Your truth and love. Quiet the chaos within, replacing it with calm assurance. Guide their mind to dwell on what is good and hopeful. Let them find rest in Your presence. Thank You for renewing their mind with Your peace. Amen.
Romans 12:2
“Be transformed by the renewing of your mind. Then you will be able to test and approve what God’s will is—his good, pleasing and perfect will.”
7. A Prayer for Joy Amid Pain
Heavenly Father, I lift up someone struggling to find joy in their depression. You are the source of true joy, and I ask that You spark light in their heart. Help them see Your beauty even in hardship. Let moments of laughter and hope break through their sorrow. Fill them with Your gladness that sustains. Guide them to find delight in Your love. Thank You for restoring their joy. Amen.
Nehemiah 8:10
“The joy of the Lord is your strength.”
8. A Prayer for Overcoming Despair
Lord, I pray for one sinking in despair’s grip. Depression feels overwhelming, but You are greater. Lift them above their hopelessness with Your mighty hand. Remind them of Your unfailing love that never abandons. Give them courage to fight another day, trusting You are with them. Replace their despair with faith in Your promises. Thank You for being their deliverer. Amen.
Psalm 34:18
“The Lord is close to the brokenhearted and saves those who are crushed in spirit.”
9. A Prayer for Restful Sleep
Dear God, I pray for someone whose depression steals their rest. Grant them peaceful sleep tonight. Calm their racing thoughts and ease their heart’s burdens. Let them lie down in safety, cradled by Your love. Protect their mind from fear and worry as they rest. Renew their strength through Your gift of sleep. Thank You for watching over them through the night. Amen.
Psalm 4:8
“In peace I will lie down and sleep, for you alone, Lord, make me dwell in safety.”
10. A Prayer for Feeling Loved
Loving Father, I pray for one who feels unloved in their depression. Let them know Your boundless love surrounds them. Help them see their worth through Your eyes. Fill their heart with assurance that they are cherished. Surround them with people who reflect Your love. Replace loneliness with the warmth of Your presence. Thank You for loving them beyond measure. Amen.
Romans 8:38-39
“For I am convinced that neither death nor life… will be able to separate us from the love of God that is in Christ Jesus our Lord.”
11. A Prayer for Courage to Seek Help
Lord, I pray for someone hesitant to seek help for their depression. Give them courage to reach out, trusting You guide their steps. Remove shame and fear, replacing them with confidence in Your care. Lead them to wise counselors and loving support. Help them see asking for help is strength, not weakness. Thank You for providing paths to healing. Amen.
Proverbs 3:5-6
“Trust in the Lord with all your heart and lean not on your own understanding; in all your ways submit to him, and he will make your paths straight.”
12. A Prayer for Trust in God’s Plan
Dear God, I lift up one struggling to trust amid depression. Help them believe Your plan is good, even when they cannot see it. Strengthen their faith to rely on Your wisdom. Let them find peace in surrendering to Your will. Guide their steps with Your light, easing their doubts. Thank You for working all things for their good. Amen.
Romans 8:28
“And we know that in all things God works for the good of those who love him, who have been called according to his purpose.”
13. A Prayer for Release from Guilt
Heavenly Father, I pray for someone burdened by guilt in their depression. Free them from self-condemnation with Your grace. Remind them Your mercy covers all. Help them forgive themselves as You have forgiven. Lift the weight of shame, filling them with Your love. Let them walk in the freedom of Your redemption. Thank You for Your endless forgiveness. Amen.
1 John 1:9
“If we confess our sins, he is faithful and just and will forgive us our sins and purify us from all unrighteousness.”
14. A Prayer for Finding Purpose
Lord, I pray for one who feels purposeless in their depression. Show them the unique calling You have for them. Ignite their heart with meaning and direction. Help them see their value in Your kingdom. Guide their steps toward fulfilling Your plan. Let them find joy in serving You and others. Thank You for giving them purpose. Amen.
Ephesians 2:10
“For we are God’s handiwork, created in Christ Jesus to do good works, which God prepared in advance for us to do.”
15. A Prayer for Patience in Healing
Dear God, I pray for someone needing patience as they heal from depression. Grant them grace to trust Your timing. Help them take each day as it comes, resting in Your care. Let them see progress, however small, as Your work in them. Strengthen their endurance with Your love. Thank You for guiding them gently toward wholeness. Amen.
Psalm 27:14
“Wait for the Lord; be strong and take heart and wait for the Lord.”
16. A Prayer for Breaking Isolation
Loving Father, I pray for one isolated by depression. Draw them out with Your love and connect them to others. Help them find safe spaces to share and be heard. Surround them with compassionate friends who reflect Your care. Ease their fear of rejection, filling them with courage. Thank You for creating them for community. Amen.
Ecclesiastes 4:9-10
“Two are better than one… If either of them falls down, one can help the other up.”
17. A Prayer for Renewed Energy
Lord, I pray for someone drained by depression’s weight. Restore their energy with Your vitality. Lift their fatigue and fill them with strength to face each day. Help them find small joys that spark life within. Let Your Spirit revive their weary soul. Thank You for being their source of endless power. Amen.
Isaiah 40:31
“But those who hope in the Lord will renew their strength. They will soar on wings like eagles.”
18. A Prayer for Protection from Negative Thoughts
Dear God, I pray for one overwhelmed by negative thoughts in depression. Guard their mind with Your truth. Replace lies with Your promises of hope and love. Help them take every thought captive to You. Fill their heart with peace that drowns out fear. Thank You for being their defender and guide. Amen.
2 Corinthians 10:5
“We take captive every thought to make it obedient to Christ.”
19. A Prayer for Gratitude in Hard Times
Heavenly Father, I pray for someone struggling to find gratitude amid depression. Open their eyes to Your blessings, however small. Help them thank You for Your presence and love. Let gratitude shift their perspective, bringing light to their heart. Fill them with hope as they count Your gifts. Thank You for Your constant goodness. Amen.
1 Thessalonians 5:18
“Give thanks in all circumstances; for this is God’s will for you in Christ Jesus.”
20. A Prayer for Faith Amid Doubt
Lord, I pray for one whose faith wavers in depression’s grip. Strengthen their belief in Your love and power. Help them cling to You, even when they feel far away. Let Your Spirit whisper truth to their soul. Guide them through doubt to a deeper trust. Thank You for holding them close always. Amen.
Mark 9:24
“I do believe; help me overcome my unbelief!”
21. A Prayer for Deliverance from Darkness
Dear God, I pray for someone lost in depression’s darkness. Be their light and lead them out. Break the chains that bind their heart and set them free. Fill them with Your hope and joy. Help them see Your goodness shining through. Thank You for being their salvation and guide. Amen.
Psalm 107:14
“He brought them out of darkness, the utter darkness, and broke away their chains.”
22. A Prayer for Acceptance of Self
Loving Father, I pray for one who struggles to accept themselves in depression. Help them see their worth as Your creation. Fill them with love for who You made them to be. Silence voices of self-doubt with Your truth. Let them embrace Your grace and forgiveness. Thank You for loving them unconditionally. Amen.
Psalm 139:14
“I praise you because I am fearfully and wonderfully made.”
23. A Prayer for Hope in Tomorrow
Lord, I pray for someone who fears tomorrow in their depression. Plant hope in their heart for a brighter future. Help them trust Your plans are good. Let them face each day with courage, knowing You are there. Fill them with expectation of Your mercy. Thank You for new beginnings. Amen.
Lamentations 3:22-23
“Because of the Lord’s great love we are not consumed, for his compassions never fail. They are new every morning.”
24. A Prayer for Letting Go of Fear
Dear God, I pray for one gripped by fear in their depression. Replace their anxiety with Your peace. Help them release their worries to You, trusting Your care. Fill their heart with courage to face the unknown. Let them rest in Your perfect love that casts out fear. Thank You for being their refuge. Amen.
1 John 4:18
“There is no fear in love. But perfect love drives out fear.”
25. A Prayer for Connection with Others
Heavenly Father, I pray for someone lonely in their depression. Open doors to meaningful connections. Help them find friends who listen and care. Let them feel Your love through others’ kindness. Ease their hesitation to reach out, filling them with trust. Thank You for creating them for relationship. Amen.
Hebrews 10:24-25
“And let us consider how we may spur one another on toward love and good deeds, not giving up meeting together.”
26. A Prayer for Physical Strength
Lord, I pray for one whose body feels weak from depression. Restore their physical strength with Your power. Help them care for themselves with rest and nourishment. Let Your healing flow through their body, renewing their energy. Fill them with vitality to face each day. Thank You for sustaining them. Amen.
Psalm 73:26
“My flesh and my heart may fail, but God is the strength of my heart and my portion forever.”
27. A Prayer for Trusting God’s Presence
Dear God, I pray for someone who feels alone in depression. Remind them You are always near. Help them sense Your presence in their quiet moments. Let them trust You walk beside them through every valley. Fill their heart with peace, knowing You never leave. Thank You for Your faithfulness. Amen.
Deuteronomy 31:8
“The Lord himself goes before you and will be with you; he will never leave you nor forsake you.”
28. A Prayer for Embracing God’s Grace
Loving Father, I pray for one who feels unworthy in their depression. Let them embrace Your grace that covers all. Help them accept Your love without earning it. Fill them with peace, knowing You delight in them. Let Your mercy wash away their doubts. Thank You for Your boundless grace. Amen.
Ephesians 2:8
“For it is by grace you have been saved, through faith—and this is not from yourselves, it is the gift of God.”
29. A Prayer for Resilience in Trials
Lord, I pray for someone facing trials in their depression. Grant them resilience to persevere. Help them lean on Your strength when theirs fails. Let them find hope in Your promises, knowing You are with them. Fill them with courage to keep going. Thank You for upholding them always. Amen.
James 1:12
“Blessed is the one who perseveres under trial because, having stood the test, that person will receive the crown of life.”
30. A Prayer for Eternal Perspective
Dear God, I pray for one whose depression clouds their view. Give them an eternal perspective, seeing beyond today’s pain. Help them trust in Your promise of heaven’s joy. Let them find comfort in Your forever love. Fill their heart with hope for what’s to come. Thank You for Your eternal promises. Amen.
2 Corinthians 4:17
“For our light and momentary troubles are achieving for us an eternal glory that far outweighs them all.”
Conclusion: Prayer For Depressed Person
Depression may feel overwhelming, but God’s light can break through even the heaviest clouds. Never forget that healing is possible, and peace is within reach through prayer and faith. Whether you’re praying for yourself or someone you love, trust that God’s grace is sufficient. Keep praying, keep hoping, and allow His love to renew your strength daily.
